Abstract
Significant developments in the isolation of tetramic acids and tetronic acids, in the elucidation of their biosyntheses and their biological activities and in laboratory syntheses are reviewed with a focus on those derivatives with medicinal and pharmacological relevance. Important new members of the title compound families isolated since the year 2000 are covered as well as new biological aspects of some earlier congeners.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Biology
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Furans / chemical synthesis
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Furans / chemistry*
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Furans / metabolism
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Furans / pharmacology*
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Humans
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Peptides / chemistry
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Pyrrolidinones / chemical synthesis
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Pyrrolidinones / chemistry*
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Pyrrolidinones / metabolism
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Pyrrolidinones / pharmacology*
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Structure-Activity Relationship
Substances
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Furans
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Peptides
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Pyrrolidinones
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tetramic acid
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tetronic acid